Trimetazidine

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Trimetazidine in AMI.

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This review summarizes the available evidence on the cardioprotective effects of trimetazidine, focusing on clinical studies in a large spectrum of patients, including those with stable angina pectoris, acute myocardial infarction, ischemic cardiomyopathy, heart failure, and those undergoing percutaneous coronary intervention. The cardioprotective effects of trimetazidine have been proven both ...

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Trimetazidine effects on oxidative damage

Trimetazidine is an anti anginal medication and ensures the proper functioning of transmembrane ionic channels by maintaining intracellular ATP production in ischemic conditions. Trimetazidine prevents the accumulation of calcium in cardiomyocytes, adjusts cellular acidosis, and decreases production of free oxygen radicals. Trimetazidine blocks long chain 3-ketoacyl coenzyme A thiolase activity...

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ژورنال

عنوان ژورنال: Reactions Weekly

سال: 2021

ISSN: ['1179-2051', '0114-9954']

DOI: https://doi.org/10.1007/s40278-021-95986-x